Compile Data Set for Download or QSAR
maximum 50k data
Found 471 of ic50 data for polymerid = 4084
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of beta-hematin formation after 18 hrs by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)
Affinity DataIC50:  12nMAssay Description:Inhibition of beta-hematin formation after 18 hrs by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50410879(CHEMBL5268777)
Affinity DataIC50:  13nMAssay Description:Inhibition of beta-hematin formation after 18 hrs by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50410891(CHEMBL5290944)
Affinity DataIC50:  20nMAssay Description:Inhibition of electric eel recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50027777(CHEBI:69919 | Hydrastine)
Affinity DataIC50: >80nMAssay Description:Inhibition of beta-hematin formation after 18 hrs by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50410885(CHEMBL5269466)
Affinity DataIC50:  160nMAssay Description:Inhibition of SiaTnTRI2-induced activation of CD69 high in human lymphocytes assessed as InsP2 productionMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM33314(pyridazinone, 2-1 | pyridazinone, 2-10)
Affinity DataIC50:  200nMpH: 7.5 T: 2°CAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50410888(CHEMBL5268517)
Affinity DataIC50:  220nMAssay Description:Inhibition of mouse recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM33374(pyrazolethione, 3-12)
Affinity DataIC50:  300nMAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50033731((R)-5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Staphylococcus aureus SrtA deltaN24 mutant transpeptidation activity using abz-LPATG-dnp as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50:  300nMAssay Description:Irreversible inhibition of recombinant Staphylococcus aureus sortase A deltaN24 expressed in Escherichia coli BL21(DE3) cells using Abz-LPATG-Dnp as ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50271717(CHEMBL4127840)
Affinity DataIC50:  360nMAssay Description:Inhibition of Staphylococcus aureus SrtA deltaN24 mutant transpeptidation activity using abz-LPATG-dnp as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50:  370nMAssay Description:Inhibition of recombinant Staphylococcus aureus sortase A deltaN24 transpeptidation expressed in Escherichia coli BL21 (DE3) cells using Abz-LPATG-Dn...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50:  400nMAssay Description:Irreversible inhibition of recombinant Staphylococcus aureus sortase A deltaN24 expressed in Escherichia coli BL21(DE3) cells using Abz-LPATG-Dnp as ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50410890(CHEMBL5290647)
Affinity DataIC50:  410nMAssay Description:Inhibition of electric eel recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50:  500nMAssay Description:Irreversible inhibition of recombinant Staphylococcus aureus sortase A deltaN24 expressed in Escherichia coli BL21(DE3) cells using Abz-LPATG-Dnp as ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50410887(CHEMBL5290303)
Affinity DataIC50:  540nMAssay Description:Inhibition of mouse recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542885(CHEMBL4641661)
Affinity DataIC50:  600nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542873(CHEMBL4646366)
Affinity DataIC50:  600nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50166940(NP-031112 | NP-12 | Tideglusib | US20230414581, Co...)
Affinity DataIC50:  600nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50410886(CHEMBL5279799)
Affinity DataIC50:  620nMAssay Description:Inhibition of human rhodamine-labelled soluble CD69 by standard plate inhibition assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542879(CHEMBL4635655)
Affinity DataIC50:  700nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542875(CHEMBL4634419)
Affinity DataIC50:  700nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM33379(pyrazolethione, 3-17)
Affinity DataIC50:  760nMAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542892(CHEMBL4638466)
Affinity DataIC50:  800nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542876(CHEMBL4647174 | US20230414581, Compound 3)
Affinity DataIC50:  800nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50410889(CHEMBL5275369)
Affinity DataIC50:  840nMAssay Description:Inhibition of mouse recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542878(CHEMBL4647001)
Affinity DataIC50:  900nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542874(CHEMBL4645185)
Affinity DataIC50:  900nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542886(CHEMBL4634267)
Affinity DataIC50:  900nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM33348(pyridazinone, 2-35)
Affinity DataIC50:  1.00E+3nMAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542884(CHEMBL4645619)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50:  1.10E+3nMAssay Description:Irreversible inhibition of recombinant Staphylococcus aureus sortase A deltaN24 expressed in Escherichia coli BL21(DE3) cells using Abz-LPATG-Dnp as ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542890(CHEMBL4633170)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542888(CHEMBL4634109)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542877(CHEMBL4646173)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542887(CHEMBL4637697)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542883(CHEMBL4643977)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM33322(pyridazinone, 2-9)
Affinity DataIC50:  1.40E+3nMAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM33330(pyridazinone, 2-17)
Affinity DataIC50:  1.50E+3nMAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542891(CHEMBL4637940)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542882(CHEMBL4639217)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542870(CHEMBL4637978)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542881(CHEMBL4633804)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50:  2.65E+3nMAssay Description:Inhibition of recombinant Staphylococcus aureus sortase A deltaN24 transpeptidation expressed in Escherichia coli BL21 (DE3) cells using IsdA64 to 32...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50542865(CHEMBL4635187)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM33322(pyridazinone, 2-9)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant Staphylococcus aureus wild type truncated C-terminal His6 tagged Srt A using Abz-Leu-Pro-Glu-Thr-Gly-Lys(Dnp)-NH2 as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM33333(pyridazinone, 2-20)
Affinity DataIC50:  3.10E+3nMAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM33327(pyridazinone, 2-14)
Affinity DataIC50:  3.30E+3nMAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)TBA
LigandPNGBDBM50030337(CHEMBL3343843)
Affinity DataIC50:  3.39E+3nMAssay Description:Inhibition of Staphylococcus aureus sortase A using dabcyl-QALPETGEE-edans as substrate incubated for 1 hr prior to substrate addition measured at 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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